Sporting marked the final home game of coach Ruben Amorim's reign in stunning fashion as Viktor Gyokeres' hat-trick saw them come from behind to thrash Manchester City 4-1 and maintain their superb start to the Champions League on Tuesday.
The three Premier League and three La Liga clubs in the last eight avoided each other, with Manchester City up against Atletico Madrid and Liverpool to face Portuguese side Benfica.
Manchester United's teenage striker Marcus Rashford struck a stunning second-half free-kick to secure a 1-0 win at Celta Vigo in their Europa League semi-final, first leg on Thursday.
Images from the English Premier League matches played on Saturday
A Roberto Firmino hat-trick proved the highlight of Liverpool's 5-1 demolition of Arsenal as the Premier League leaders opened a nine-point gap over Tottenham Hotspur, who lost 3-1 to Wolverhampton Wanderers.
Manchester City have won many admirers in their 'wonder season' but need more trophies to be considered the best Premier League team ever, ex-Manchester United winger Ryan Giggs has said.
Manchester United stayed in fifth place, one point above West Ham, but it was another depressingly dull day at Old Trafford where United were booed off after losing 1-0 to Southampton.
Guardiola beat out Chelsea's Antonio Conte, Burnley's Sean Dyche, Liverpool's Juergen Klopp, Manchester United's Jose Mourinho and Arsenal's Arsene Wenger for the award.
Liverpool substitute Adam Lallana struck deep into stoppage time to snatch a 5-4 win over shell-shocked Norwich City in an extraordinary Premier League game at Carrow Road on Saturday.
Ole Gunnar Solskjaer continued his dream start as Manchester United caretaker manager with a 3-1 Premier League win over Huddersfield on his Old Trafford debut in the dugout on Wednesday.
The chants of 'Are you watching Merseyside?' began as soon as Wayne Rooney scored a penalty to earn Manchester United a 1-1 draw at Blackburn Rovers on Saturday to seal their record 19th English league title.
Manchester United interim manager Ole Gunnar Solskjaer said it would be 'strange' if he is not in charge at Old Trafford next season after being part of their promotional campaign to sell season tickets.
IMAGES from the Premier League matches played on Saturday.
IMAGES from the Champions League matches played on Tuesday
Liverpool manager Juergen Klopp is not about to change his team's trademark style against Champions League quarter-final opponent
Images from the English Premier League matches played on Saturday
Images from football matches played across Europe over the weekend.
FIFA president Gianni Infantino told the 12 breakaway European Super League clubs on Tuesday that they could not be "half in, half out" of the established football system and must face up to the reality of their decision.
Liverpool cranked up the pressure on West Ham United manager Slaven Bilic with a 4-1 victory at the London Stadium, while Burnley's remarkable start to the Premier League season continued thanks to a 1-0 victory at Southampton on Saturday.
Liverpool will attempt to sweep away the January blues on the last day of a wretched month when they host commanding Premier League leaders Chelsea at Anfield on Tuesday.
Discarded striker Danny Welbeck returned to demolish Manchester United's hopes of silverware by netting the winner in Arsenal's 2-1 FA Cup quarter-final victory at Old Trafford on Monday.
Manchester United skipper Harry Maguire has received a bomb threat to his home in Cheshire with local police conducting a sweep of the venue
Wayne Rooney scored two first half goals to help send Manchester United to a 4-1 win over a spirited Aston Villa on Saturday, temporarily lifting the gloom surrounding David Moyes' dismal first term in charge.
Mario Balotelli will return to Liverpool's squad for the festive programme but manager Brendan Rodgers was hardly effusive in his praise of the Italy's striker's credentials.
London clubs' erratic start to the Premier League season improved with victories for Chelsea, Tottenham Hotspur and Arsenal on Saturday but Manchester sides continued to make the running, with City and United the top two.
Liverpool opened up a seven-point gap at the top of the English Premier League with a 1-0 win at Brighton & Hove Albion on Saturday, while Arsenal's poor away form continued with a 1-0 defeat at West Ham United.
World champions France had eight players, one less than former holders Spain, in international players' association FIFPro's 55-name shortlist for its World XI of 2018 award.
A Sergio Aguero hat-trick helped Manchester City get back to winning ways in the Premier League with a 3-1 victory over Newcastle United, as they stayed 12 points ahead of Manchester United who had to dig deep to secure a 1-0 win at Burnley.
Theo Walcott's double fired Arsenal back to the top of the Premier League as the Gunners got their title challenge back on track with a 3-1 victory at West Ham United on Thursday.
IMAGES from English Premier League matches played on Sunday.
Manchester United enjoyed perhaps their finest performance.
Liverpool's Mohamed Salah ended his Premier League goal drought in style by scoring twice as the champions raided the capital again to crush West Ham United 3-1 on Sunday.
Champions Leicester City will begin their Premier League title defence with a trip to newly promoted Hull City on August 13, according to the 2016-17 fixtures released on Wednesday.
"And you need also that you can make tactical choices. We are looking for the right player for our squad and (he) has to match our sporting criteria but also our financial criteria."
Manchester United could be without defender Rio Ferdinand while AS Roma will definitely be without striker Francesco Totti when the teams meet in the second leg of their Champions League quarter-final on Wednesday.
Images from the English Premier League matches played on Wednesday
Chelsea have topped the spending list with Manchester United not far behind, but West Ham United's business epitomises the TV riches which give all Premier League clubs spending power that only the elite teams in Spain or Germany can dream of.
The brilliance of Chelsea's Eden Hazard ended Liverpool's 100 percent start to the season as Maurizio Sarri's side enjoyed a 2-1 win at Anfield in the League Cup third round on Wednesday.
Imperious Liverpool extended their Premier League home winning streak against Arsenal to six on Saturday with an easy 4-0 victory that lifted them to second in the table.
The injury to the Chile forward, who was left out of the squad for Tuesday's Champions League victory over Young Boys, "will require further investigation to confirm its severity", the club added.